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Allele : Dnmt1<tm7.1Jrc> DNA methyltransferase 1; targeted mutation 7.1, Richard Chaillet
Primary Identifier  MGI:5752875 Allele Type  Targeted
Gene  Dnmt1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 13 was replaced with a floxed neomycin resistance cassette and a modified exon 13 in which nucleotide substitutions replaced the VPV sequence with three glutamic acids within the mouse-rat differential region of the intrisically disordered domain (IDD). Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Dnmt1<EEE>,
  • Dnmt1<EEE>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories

Trail: Allele




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