| Primary Identifier | MGI:5755639 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Rab11fip3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele from project Rab11fip3-7419J-M4978 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences TCAGCTGGATGAAAGCACAC, GTGCAGCTCCACAAGCCAGC, CAGTCAGTAGGCAGCTATGG, and AACAAAAATAATAATCTCGA, which resulted in a 362 bp deletion spanning exon 4 beginning at Chromosome 17 negative strand position 26,016,187 bp, GCTGCCTACTGACTGTCCAT, and ending after TGTGGAGCTGCACCTGTGTG at 26,015,826 bp (GRCm38/mm10). This mutation deletes exon 4 and 150 bp of flanking intronic sequence including the splice acceptor and donor. This mutation is predicted to result in a change in amino acid sequence after residue 594 and early truncation 14 amino acids later. |
