| Primary Identifier | MGI:5763073 | Allele Type | Targeted |
| Attribute String | Reporter | Gene | Hras |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | ES cells containing Hrastm1Xbr were retargeted to introduce a G to A and an A to C substitutions at the first and last bases of codon 12 of exon 1. This results in an amino acid substitution of serine for glycine. Cre-mediated recombination was used to remove the hygro STOP cassette. The final allele contains the G12S mutation and the IRES-beta-geo cassette. |
