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Allele : Serpine1<tm1.1Vlp> serine (or cysteine) peptidase inhibitor, clade E, member 1; targeted mutation 1.1, Victoria A Ploplis

Primary Identifier  MGI:5763484 Allele Type  Targeted
Gene  Serpine1 Transmission  Germline
Strain of Origin  C57BL/6 x 129 Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 3 was replaced with a modified one in which nucleotide substitutions result in the amino acid substitutions of alanine for arginine at position 101 (R101A) and lysine for glutamine at position 123 (Q123K). Flp-mediated recombination removed the FRT- and loxP-flanked neomycin resistance cassette inserted downstream of the modified exon 3.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • PAI-1<R101A/Q123K>,
  • PAI-1<R101A/Q123K>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele