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Allele : Rpe65<tm2.1Tmr> retinal pigment epithelium 65; targeted mutation 2.1, T Michael Redmond

Primary Identifier  MGI:5770317 Allele Type  Targeted
Attribute String  Hypomorph Gene  Rpe65
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 2 was replaced with one in which a T to C point mutation results in the amino acid substitution of leucine for proline at position 25 (P25L). Cre-mediated recombination removed the floxed selection cassette inserted downstream of the modified exon 2.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Rpe65<P25L>,
  • Rpe65<P25L>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele