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Allele : Pik3ca<tm2.1Rps> phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; targeted mutation 2.1, Ramon Parsons
Primary Identifier  MGI:5776388 Allele Type  Targeted
Attribute String  Not Specified Gene  Pik3ca
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 20 was replaced with a floxed splice acceptor/neomycin resistance cassette and a modified exon 20 in which a A to G mutation results in the amino acid substitution of arginine for histidine at position 1047 (H1047R). Cre-mediated recombination removed the selection cassette.
  • mutations:
  • Single point mutation,
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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