Primary Identifier | MGI:5779547 | Allele Type | Transgenic |
Attribute String | Transactivator | Gene | Tg(PMP22-tTA)JY13Clh |
Strain of Origin | (C57BL/6J x CBA/Ca)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The tTA open reading frame was introduced into the second exon of the human PMP22 gene on YAC 49G7 such that the start of translation of the PMP22 gene is used to start the tTA ORF. The PMP22 genen on the YAC is disrupted and is not expressed. tTA is expressed in Schwann cells. |