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Allele : Rorb<tm2.1(tTA2)Hze> RAR-related orphan receptor beta; targeted mutation 2.1, Hongkui Zeng
Primary Identifier  MGI:5784556 Allele Type  Targeted
Attribute String  Transactivator Gene  Rorb
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector contains, from 5' to 3',a partial Rorb intron 9 containing an FRT3 site, a partial Ndnf exon 10 sequence up to (but not including) the endogenous stop codon, a T2A sequence that is in-frame with the Rorb coding sequence,a synthetic modified tetracycline-regulated transactivator (tTA2) gene, polyA signal, an AttB site, a PGK-Neo-polyA cassette, an FRT5 site, an mRNA splice acceptor, the 3' portion of the hygromycin gene with SV40 polyA signal, and an AttP site. PhiC31-mediated recombination removed the AttB/AttP-flanked sequence (PGK-Neo-polyA::FRT5::RNA splice acceptor::3'hygro-polyA) and replaced it with the recombined AttB/AttP site (AttL).
  • mutations:
  • Insertion
  • synonyms:
  • Rorb-2A-tTA2-D,
  • Rorb-2A-tTA2-D
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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