Primary Identifier | MGI:5784924 | Organism | mouse, laboratory |
Chromosome | 2 | Mgi Type | lincRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within with a positive effect on gene expression and homeostasis of number of cells within a tissue. Acts upstream of or within with a negative effect on insulin secretion. Acts upstream of or within several processes, including insulin metabolic process; response to glucose; and type B pancreatic cell development. Located in nucleus. Is expressed in several structures, including gut; heart; hindbrain; liver; and lung. PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired glucose homeostasis, insulin resistance and decreased beta cells. [provided by MGI curators] |