Primary Identifier | MGI:5788680 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Bbs10 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A koxP site was inserted upstream of the 2-exon gene and a second loxP site, an FRT site, a neomycin selection cassette, a third loxP site and a second FRT site were inserted downstream of the gene. The neo cassette was removed through subsequent Flp-mediated recombination and the gene was deleted through Cre-mediated recombination. No detectable mRNA is expressed from this allele in samples derived from kidney and eye of homozygous mice. |