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Allele : Ercc5<tm1.2Jhjh> excision repair cross-complementing rodent repair deficiency, complementation group 5; targeted mutation 1.2, Jan H J Hoeijmakers
Primary Identifier  MGI:5787631 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ercc5
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 3. Western blot analysis confirmed the absence of protein expression in dermal fibroblasts.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Xpg<->,
  • Xpg<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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7 Publication categories

Trail: Allele




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