Primary Identifier | MGI:5790985 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cd82 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette with a 5 loxP site was inserted upstream of exon 5. An additional loxP site was inserted downstream of exon 6. Cre-mediated recombination removed the selection cassette and exons 5 and 6. Western blot analysis confirmed the absence of protein expression in the spleen, T cells, B cells and dendritic cells. |