| Primary Identifier | MGI:5789592 | Allele Type | Chemically induced (ENU) |
| Attribute String | Not Specified | Gene | Rorc |
| Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Beutler Mutagenetix |
| molecularNote | ENU-induced G to A transition at base pair 94,387,193 (v38) on chromosome 3, or base pair 14,479 in the GenBank genomic region NC_000069. The mutation corresponds to residue 241 in the mRNA sequence NM_011281 within exon 3 of 11 total exons and residue x in the mRNA sequence NM_001293734 within exon 2 of 10 total exons. The mutation results in a cysteine (C) to tyrosine (Y) substitution at position 48 (C48Y) in the RAR-related orphan receptor gamma (RORgamma1) protein and a cysteine to tyrosine substitution at position 27 in the RORgammat protein. |
