Primary Identifier | MGI:5789597 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Slfn2 |
Inheritance Mode | Recessive | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced A to T transversion at base pair 83,069,564 (v38) on chromosome 11, or base pair 4,453 in the GenBank genomic region NC_000077 for the Slfn2 gene. The mutation corresponds to residue 550 in the mRNA sequence NM_0011408 within exon 2 of 2 total exons. The mutation results in a histidine (H) to leucine (L) substitution at position 123 (H123L) in the protein. |