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Allele : Dll1<tm7(Dll1)Gos> delta like canonical Notch ligand 1; targeted mutation 7, Achim Gossler

Primary Identifier  MGI:5790965 Allele Type  Targeted
Attribute String  Hypomorph, Inserted expressed sequence, Null/knockout Gene  Dll1
Transmission  Germline Strain of Origin  129S1/SvImJ
Is Recombinase  false Is Wild Type  false
molecularNote  A minigene containing the coding sequence of the inserted gene was coupled to genomic sequence containing the last three exons (3' part of exon 9 through entire exon 11) of the host gene. This combined sequence followed by a loxP-flanked neomycin resistance gene cassette was inserted at the ATG translation start site of the host gene. This allele was used as a hypomorph because the still present neo cassette attenuates the expression of the inserted gene.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Dll1<Dll1ki+neo>,
  • Dll1<Dll1ki+neo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele