| Primary Identifier | MGI:5800483 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inducible, Inserted expressed sequence | Gene | Tg(Myh6*/tetO-SCN5A*F1759A)#Marx |
| Strain of Origin | Not Specified | Induced With | doxycycline/tetracycline |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A FLAG-tagged human SCN5A cDNA with the F1759A mutation in the local anesthetic binding site is under the control of a tetracycline-inducible modified murine alpha-MHC promoter. This mutation results in lidocaine-resistance and causes window current and persistent sodium current. Four lines were established however, the pound symbol (#) is used when line is not specified and/or lines are pooled. |
