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Allele : Lancl2<em1Vdd> LanC (bacterial lantibiotic synthetase component C)-like 2; endonuclease-mediated mutation 1, Wilfred van der Donk

Primary Identifier  MGI:5804215 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Lancl2
Strain of Origin  FVB/NHsd Is Recombinase  false
Is Wild Type  false
molecularNote  Pronuclear-stage embryos were targeted with a zinc finger nuclease pair designed to target exon 4. A founder mouse was identified carrying a 2-bp deletion at the targeted site (GAACTGCTGTatGGACGAGC -> GAACTGCTGTGGACGAGC), creating a reading-frame shift. Absence of the protein was confirmed by immunoblot analysis.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele