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Allele : Adar<tm1.1Xen> adenosine deaminase, RNA-specific; targeted mutation 1.1, Taconic Biosciences
Primary Identifier  MGI:5805648 Allele Type  Targeted
Gene  Adar Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  An F3 site flanked puromycin resistance cassette was inserted upstream of exon 7. Exon 9 was replaced with a modified one in which nucleotide substitutions (GAA to GCT) that result in the amino acid substitution of glutamic acid with alanine at position 861 (p.E861A). This mutation is predicted to produce a catalyticly inactivated protein. Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Adar1<E861A>,
  • Adar1<E861A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

11 Publication categories

Trail: Allele




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