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Allele : Tg(Pdgfrb-cre/ERT2)6096Rha transgene insertion 6096, Ralf H Adams
Primary Identifier  MGI:5807436 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Pdgfrb-cre/ERT2)6096Rha
Strain of Origin  (C57BL/6 x 129)F1 Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP24-62H17TJ) containing the entire murine platelet-derived growth factor receptor, beta polypeptide (Pdgfrb) gene. This BAC was modified to insert a creER fusion gene (a cre recombinase fused to a human estrogen receptor ligand-binding domain) into the start codon of Pdgfrb to drive expression in mural cells. The other genes on the BAC (Camk2a, Slc6a7, Cdx1, Csf1r, and Hmgxb3) are still present in the construct.
  • mutations:
  • Insertion
  • synonyms:
  • PDGFR-beta<iCre>,
  • Pdgfrb(BAC)-CreERT2,
  • PDGFR-beta<iCre>,
  • Pdgfrb(BAC)-CreERT2
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0 Mutation Involves

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