Primary Identifier | MGI:5811648 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(11Gast-Hsd17b1)5Brd |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was targeted into the Gast gene and a second loxP site was targeted into the Hsd17b1 gene. Transient expression of Cre recombinase in ES cells resulted in recombination between the two loxP sites on the same chromosome, deleting the 1 Mb region from Gast to Hsd17b1. |