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Allele : Ddr2<tm1b(EUCOMM)Wtsi> discoidin domain receptor family, member 2; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:5806884 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ddr2
Transmission  Germline Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 169825258 of Chromosome 1 upstream of exon 8 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 8 at position 169826185. A knockout reporter allele was created by cre recombinase expression in mice removing exon 8 and the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ddr2<lacZ>,
  • Ddr2<lacZ>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

10 Publication categories

Trail: Allele