Primary Identifier | MGI:5810125 | Allele Type | Targeted |
Attribute String | Conditional ready | Gene | Lias |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
description | ES cell line - Chemicon B/6N |
molecularNote | The targeting vector consists of a loxP site, the 3' UTR sequence of the bovine growth hormone gene, a neomycin cassette and a loxP site followed by the 3'-UTR sequence of the cFos gene. The bovine growth hormone gene 3'-UTR sequence directs expression of the endogenous Lias creating a hypermorph allele. Expression is 150% of endogenous gene expression. |