| Primary Identifier | MGI:5817176 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Clptm1l |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele from project Clptm1l-8201J-M4248 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GCCCAAGCTCACCCTCTGAG, GTTTCCTAACGGGACCCCAG, ACTGCAATCTAAGGGCAGCG and ATAGCATTGTATGTAGAGTG, which resulted in a 377 bp deletion beginning at Chromosome 13 positive strand position 73,604,838 bp GAGAGGTAGCCCTCAGATTG, and ending after ATCTAAGGGCAGCGTGGTTT at 73,605,214 bp (GRCm38/mm10). This mutation deletes exon 2 and 441 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 54 and early truncation 2 amino acids later. |
