|  Help  |  About  |  Contact Us

Allele : Il33<tm1.1Rlee> interleukin 33; targeted mutation 1.1, Richard T Lee

Primary Identifier  MGI:5818149 Allele Type  Targeted
Attribute String  Conditional ready Gene  Il33
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The parental targeting vector (KOMP Project ID CSD26735) composed of an FRT site followed by lacZ sequence and a loxP site, and neomycin under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site is inserted into intron 4 of the gene. A third loxP site is inserted downstream of the targeted exons 5, 6 and 7. A "conditional ready" (floxed) allele was created by flp recombinase expression in mice carrying the parental allele, removing lacZ and neo and first loxP site and leaving single FRT site in intron 4 and loxP flanked exons 5, 6 and 7.
  • mutations:
  • Insertion
  • synonyms:
  • Il33<flox>,
  • Il33<flox>
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

16 Publication categories

Trail: Allele