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Allele : Kit<tm1.2Ccai> KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.2, Chen-Leng Cai
Primary Identifier  MGI:5818517 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Kit
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A LoxP-4XPolyA-LoxP-H2B-tdTomate-FRT-Neo-FRT cassette was targeted to the start codon of kit locus with disruption of endogenous ATG by homologous recombination in ES cells. Flp-mediated recombination removed the neo selection cassette, leaving a single FRT site behind. Resulting mouse line was crossed with Protamine-Cre mice to remove 4xPloyA stop cassette.
  • mutations:
  • Insertion
  • synonyms:
  • c-kit<H2B-tdTomato>,
  • c-kit<H2B-tdTomato>
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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