|  Help  |  About  |  Contact Us

Allele : Kit<tm3.1(cre/Esr1*)Ccai> KIT proto-oncogene receptor tyrosine kinase; targeted mutation 3.1, Chen-Leng Cai
Primary Identifier  MGI:5818536 Allele Type  Targeted
Attribute String  Inducible, Null/knockout, Recombinase Gene  Kit
Transmission  Germline Strain of Origin  129
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  A cassette encoding cre recombinase fused to 2 mutated murine estrogen receptor ligand-binding domains (Mer; Esr1*) followed by FRT flanked neo selection cassette are inserted into the start codon of kit locus with disruption of endogenous ATG by homologous recombination in ES cells. Flp-mediated recombination removed the neo selection cassette, leaving a single FRT site behind.
  • mutations:
  • Insertion
  • synonyms:
  • c-kit<MerCreMer>,
  • c-kit<MerCreMer>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

Trail: Allele

3 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom