| Primary Identifier | MGI:5819376 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Wwox |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 1 and an FRT site flanked neomycin resistance gene cassette and a further loxP site were inserted in intron 1. Exon 1 and the neo cassette were removed through subsequent cre-mediated recombination, creating a null allele. Western blots confirm absence of protein product from the null allele in homozygous mice. |