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Allele : Crh<tm2.2Maj> corticotropin releasing hormone; targeted mutation 2.2, Joseph Majzoub
Primary Identifier  MGI:5823156 Allele Type  Targeted
Attribute String  Null/knockout Gene  Crh
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was introduced to intron 1 and a FRT-flanked neomycin cassette followed by a loxP site was placed in intron 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 2 floxed. Cre-mediated recombination removed exon 2. Immunohistochemistry of hypothalamus tissues confirmed that no protein was expressed in mutant mice.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Crh dl,
  • Crh dl
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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