| Primary Identifier | MGI:5824227 | Allele Type | Targeted |
| Attribute String | Conditional ready, Hypomorph | Gene | Tbc1d1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 4 was targeted with (a) point mutation(s) resulting in an S231A codon change. A loxP site and an FRT site flanked neomycin resistance gene cassette were inserted into intron 3 and a further loxP site into intron 4. The neo cassette was removed through flp-mediated recombination. This leaves modified exon 4 floxed. The codon change prevents phosphorylation of amino-acid 231 in the translated peptide. |
