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Allele : Erc1<tm1Ksak> ELKS/RAB6-interacting/CAST family member 1; targeted mutation 1, Kenji Sakimura

Primary Identifier  MGI:5827582 Allele Type  Targeted
Gene  Erc1 Transmission  Germline
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  An FRT site flanked neomycin resistance gene cassette was inserted into intron 1. Exon 1 was targeted with two codon changes: a silent mutation of L54 (CTT to CTG) and an S55A (TCA to GCC) mutation. These mutations create a diagnostic MscI restriction site and changes serine 55 to an alanine, thus preventing phosphorylation of the peptide at that position.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • ELKS<S55A>,
  • ELKS-S55A,
  • ELKS-S55A,
  • ELKS<S55A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele