| Primary Identifier | MGI:5827583 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Trex1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Exon 2 was floxed. A human cDNA containing the V235fs mutation was knocked in. This mutation creates a dominant frameshift mutation that truncates the C terminus and is associated with retinal vasculopathy with cerebral leukodystrophy. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. |
