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Allele : Ocln<tm1.1Alpl> occludin; targeted mutation 1.1, Alexander Ploss

Primary Identifier  MGI:5828874 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Ocln
Transmission  Germline Strain of Origin  129S6/SvEv
Is Recombinase  false Is Wild Type  false
molecularNote  To create a hepatitis C virus uptake model, the part of exon 3 encoding extracellular loop 2 (EL2) was replaced with the equivalent part of exon 3 of the human orthologue. A loxP site flanked neomycin resistance gene cassette was inserted into human intron 3. This neo cassette was removed through subsequent cre-mediated recombination.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • mOCLN/hEL2,
  • mOCLN/hEL2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele