Primary Identifier | MGI:5882799 | Allele Type | Targeted |
Attribute String | Humanized sequence | Gene | Clcn7 |
Transmission | Germline | Strain of Origin | C57BL/6N-A<tm1Brd> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An F316L (CTT->CCT) missense mutation (corresponding to the human F318L mutation) and loxP-flanked neomycin cassette are introduced to exon 11 of the gene via homologous recombination. Cre-mediated recombination removed the floxed neo cassette. |