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Allele : Nfatc1<tm1Akpa> nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; targeted mutation 1, Amiya Kumar Patra

Primary Identifier  MGI:5882714 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Nfatc1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site, a neomycin resistance gene cassette and a second loxP site were inserted upstream of the alternative P2 promoter in intron 1. A third loxP site was inserted downstream of the promoter. This creates a conditional-ready isoform specific knock-out allele which, upon cre-mediated recombination, would abolish transcription of the betaA, betaB and betaC splice variants.
  • mutations:
  • Insertion
  • synonyms:
  • Nfatc1 P2<fl>,
  • Nfatc1 P2<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

3 Publication categories

Trail: Allele