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Allele : Mgll<tm1.1Crv> monoglyceride lipase; targeted mutation 1.1, Benjamin F Cravatt

Primary Identifier  MGI:5883232 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Mgll
Transmission  Germline Strain of Origin  B6.Cg-Thy1<a>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 4. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with a floxed exon 4. This exon codes for the catalytic Ser122 residue.
  • mutations:
  • Insertion
  • synonyms:
  • Mgll<loxP>,
  • MAGL<loxP>,
  • Mgll<loxP>,
  • MAGL<loxP>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele