Primary Identifier | MGI:5888730 | Allele Type | Targeted |
Attribute String | Conditional ready, Null/knockout, Reporter | Gene | Map3k13 |
Transmission | Germline | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Knockout mice were generated at Ingenious Targeting Laboratory by electroporating a targeting construct obtained from the KOMP repository. An FRT-flanked gene trap vector was inserted into intron 1 and loxP sites flanked exon 2. A capillary-based immunoassay demonstrated the absence of MAP3K13 expression in retinal ganglion cells (RGCs) isolated from homozygous mutant mice at 24 hrs after immunopanning injury. |