| Primary Identifier | MGI:5888857 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Paxx |
| Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | All coding exons of the gene and part of the non-coding exon 1 were replaced by a Neomycin resistance (NeoR) cassette flanked by frt sequences. Chimeras were bred with mice expressing FLIPase constitutively to remove the Neo cassette and generate the recombined allele. Western blotting validated the absence of PAXX protein in murine embryonic fibroblasts derived from homozygous mutant mice. |
