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Allele : Rdh10<tm1Eper> retinol dehydrogenase 10 (all-trans); targeted mutation 1, Edgar M Pera

Primary Identifier  MGI:5896958 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Rdh10
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 2 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 4. This creates a conditional-ready allele with exons 3 and 4 floxed. Upon cre-mediated recombination these two exons, coding for the active site of the enzyme, would be deleted, also causing a frameshift in the downstream exons.
  • mutations:
  • Insertion
  • synonyms:
  • Rdh10<F>,
  • Rdh10<F>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele