| Primary Identifier | MGI:5897819 | Allele Type | Endonuclease-mediated |
| Attribute String | Hypomorph | Gene | Rabep2 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology targeting is used to introduce a nucleotide substitution R298Q (guanine to adenine) at position rs33080487 in the Rabep2 gene. Gene product is detected by western blot analysis (with mass spectrometry confirmation) of whole brain and neocortex tissue. The nucleotide substitution reflects a polymorphism (adenine) found in the BALB/cByJ inbred strain, in contrast to guanine found in C57BL/6 mice. |
