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Allele : Mirc30<tm1Wtsi> microRNA cluster 30, including Mir16-1 through Mir15a; targeted mutation 1, Wellcome Trust Sanger Institute
Primary Identifier  MGI:5898499 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mirc30
Transmission  Cell Line Strain of Origin  C57BL/6N-A<tm1Brd>
Is Recombinase  false Is Wild Type  false
Project Collection  Sanger miRNA knockouts
molecularNote  The cluster of microRNA genes was replaced via homologous recombination by a LoxP-F3-PGK-EM7-Purotk-bpA-LoxP-FRT targeting vector with 5.5kb (5') and 3.3kb (3') arms of homology. Briefly, this is a puromycin/thymidine kinase fusion gene under the control of EM7/PGK promoters and flanked by LoxP and F3/FRT sites.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • Mir16-1<tm1(mirKO)Wtsi>,
  • Mir16-1<tm1(mirKO)Wtsi>,
  • Mir16-1/Mir15a cluster 14N1 KO,
  • Mir16-1/Mir15a cluster 14N1 KO,
  • Mir16-1/Mir15a cluster 14N1 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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