|  Help  |  About  |  Contact Us

Allele : Tg(CAG-Nos1ap)112Achak transgene insertion 112, Aravinda Chakravarti
Primary Identifier  MGI:5903441 Allele Type  Transgenic
Attribute String  Inserted expressed sequence, Reporter Gene  Tg(CAG-Nos1ap)112Achak
Strain of Origin  FVB/NJ Is Recombinase  false
Is Wild Type  false
molecularNote  The CAG promoter drives the expression of floxed lacZ followed by three polyadenylation (pA) signals. Following this is the Nos1ap open reading frame (ORF, NM_001109985) including start and stop codons; this is then followed by an IRES-puromycin-pA cassette. In the presence of cre recombinase, the floxed lacZ-polyA cassette is deleted, leaving Nos1ap under the control of the strong constitutive enhancer-promoter element. This leads to Nos1ap overexpression in the tissues in which cre recombinase is expressed. Lines 112, 314 and 333 were generated.
  • mutations:
  • Insertion
  • synonyms:
  • Nos1ap<Tg>,
  • Nos1ap<Tg>
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom