| Primary Identifier | MGI:5911684 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Sst-mCherry,-icre)44Fmgb |
| Strain of Origin | Not Specified | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | A sequences coding for mCherry and improved cre recombinase gene (icre) separated by a viral T2A-sequence to allow bicistronic expression replaced the coding sequence between the start codon in exon 1 and the stop codon in exon 2 in the murine based bacterial artificial chromosome (BAC bQ73b10). Initially 4 founders (SST-Cre33, -38, -43 and -44) were generated, of which SST-Cre-43 failed to pass on the transgene. Subsequencty, two strains (SST-Cre33 and -38) lost this positive reporter expression. Only the remaining strain SST-Cre-44 was eventually crossed back into a C57B6 background for eight generations. |
