| Primary Identifier | MGI:5911525 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Gabrg3 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GGAGCTACCAAGGTAAACAC, ATTTAGGGTTGTGTACTCAT, GTTACTGGCAATTTGCAGTG and GCCTGTGTTGTTAGTGGCTG, which resulted in a 621 bp deletion beginning at Chromosome 7 negative strand position 57,323,993 bp and ending after 57,323,373 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000490283 (exon 3) and 553 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 67 and early truncation 4 amino acids later. |
