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Allele : Gabrb3<tm2.1Uru> GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3; targeted mutation 2.1, Uwe Rudolph
Primary Identifier  MGI:5908395 Allele Type  Targeted
Attribute String  Not Specified Gene  Gabrb3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  The codons for serines 408 and 409 in exon 9 were mutated to alanine and a loxP and FRT flanked neo cassette was inserted upstream of the 5' end of exon 9 via homologous recombination. Cre-mediated recombination removed the neo cassette. Cell surface expression of this subunit is increased to 145% of wild-type without modifying total subunit expression levels.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • S408/9A,
  • S408/9A
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

6 Publication categories

Trail: Allele




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