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Allele : Flicr<em2Doi> Foxp3 regulating long intergenic noncoding RNA; endonuclease-mediated mutation 2, Christophe Benoist and Diane Mathis

Primary Identifier  MGI:5908597 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Flicr
Strain of Origin  NOD Is Recombinase  false
Is Wild Type  false
molecularNote  Using an sgRNA (5'-GCAAGACTGGCTTCAGGCCTG-3') targeting the exon 3 splice acceptor site with CRISPR/Cas9, an allele with a 12 bp deletion of that site was created. Exon 3 has high homology to the human ortholog and its splice site is conserved. Only one progeny was born.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele