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Allele : Ptk2b<tm1.1Geno> PTK2 protein tyrosine kinase 2 beta; targeted mutation 1.1, Genoway

Primary Identifier  MGI:5911061 Allele Type  Targeted
Attribute String  Null/knockout Gene  Ptk2b
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  LoxP sites were inserted to flank exons 15-18 and an frt-flanked neomycin selection cassette. Cre-mediated recombination in the germ line resulted in a deletion of the genomic region containing exons 15-18. These exons encode the kinase domain. Western blot and immunohistochemistry studies showed that no detectable encoded protein is expressed from this allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Pyk2<->,
  • Pyk2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele