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Allele : Optn<tm1.2Arte> optineurin; targeted mutation 1.2, TaconicArtemis
Primary Identifier  MGI:5911097 Allele Type  Targeted
Attribute String  Null/knockout Gene  Optn
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site and FRT flanked neo cassette was inserted in intron 11, an Asp to Asn mutation was introduced at position 477 in exon 12, and a loxP site was inserted in intron 12 via homologous recombination. Flp-mediated recombination removed the neo cassette. Cre mediated recombination deleted exon 12.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Optn<deltaEx12>,
  • Optn<deltaEx12>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories

Trail: Allele




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