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Allele : Tg(Myh6-LPL*)357Ijg transgene insertion 357, Ira J Goldberg
Primary Identifier  MGI:5907463 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Myh6-LPL*)357Ijg
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The human gene ligated to a glycosylphosphatidylinositol (GPI) anchor is under the control of the alpha myosin heavy chain promoter. The GPI anchors the LPL to the cardiomyocyte surface. Northern blot analysis confirmed high expression of the transgene only in the heart. Hearts, but not post-heparin plasma, contains human lipoprotein lipase activity. Three lines were generated; 346, 357, and 358.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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