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Allele : Kcnma1<tm1.1Alme> potassium large conductance calcium-activated channel, subfamily M, alpha member 1; targeted mutation 1.1, Andrea L Meredith
Primary Identifier  MGI:5911897 Allele Type  Targeted
Attribute String  Conditional ready, No functional change, Reporter Gene  Kcnma1
Transmission  Germline Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A lox71 site was inserted upstream of exon 2 and an FRT flanked neo cassette, 2A-tdTomato gene and lox66 site in inverse orientation were inserted downstream of exon 2. Flp mediated recombination removed the neo cassette. In the absence of cre-mediated recombination the tdTomato reporter is not expressed. Following cre-mediated the tdTomato reporter is expressed and exon 2 is placed in inverse orientation. The cre-mediated inversion is irreversible.
  • mutations:
  • Insertion
  • synonyms:
  • Kcnma1<fl>,
  • Kcnma1<fl>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

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Trail: Allele




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