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Allele : Tg(Myh6-Ptpn11*Q510E)#Krnz transgene insertion, Maike Krenz

Primary Identifier  MGI:5909086 Allele Type  Transgenic
Attribute String  Dominant negative, Inserted expressed sequence Gene  Tg(Myh6-Ptpn11*Q510E)#Krnz
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The murine alpha-myosin heavy chain promoter drives the expression of a Ptpn11 cDNA which contains the amino acid substitution of glutamate for glutamine at position 510 (Q510E). Q510E is a dominant-negative loss-of-function mutation. The pound symbol (#) is used when line is not specified and/or lines are pooled.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele